So I have a 1988 4Runner came stock with low impedance injectors, I purchased a set a remained Bosch 4 hole 195cc high impedance injectors, I am having a serious mental block right now and need some help with the wiring that needs to be done to delete the solenoid resistor.

 

CAN you substitute high impedance injectors with your ECM?

I don't know. The hot rod forums talk about "peak and hold" signals from the ECM to fire low impedance injectors. But this site: http://fuelinjectorclinic.com/faqs/#9 suggests that ECM's matched to a resistor box don't use peak and hold, and the the resistor box is there to just fool the ECM into thinking it's looking at high impedance injectors.

As I said, I don't know.