i am planning on buying a 1980s Nissian 200sx and the motor and tranny are no good so i wanna swap a toyota 22re is this possible and any tips

 

anything is possible with enough $$$$$$

 

Why ?? If you want to go Toyota 4 Cylinder why not go newer like the 3RZ

Now merging the two different manufactures wiring harnesses will be an experience

Depending if you can do all the fabricating and electrical work have of budget of @ $10,000.00 to start

You will be off to a good start